Miami Cruises MIAMI CRUISES

Cruise from Miami to Panama Canal 2022

Discover the best of the Panama Canal on a luxury cruise vacation out of Miami. As one of the 7 Wonders of the Modern World, the Panama Canal is a must-see cruise destination and something you'll remember for a lifetime. The Panama Canal is a 48-mile ship canal that connects the Atlantic Ocean to the Pacific Ocean. The Panama Canal cruise season typically runs from October to April. Depart from various cities including Miami, cruise to some of the most exotic and beautiful destinations on Earth, visit Panama and see the beaches, islands, rainforests and architecture. Discover white sandy beaches and explore this tropical paradise with tours and excursions at its breathtaking ports of call on your next cruise vacation to the Panama Canal.

Panama Canal from Miami

Panama Canal cruises are available all year long, making for a convenient way to get away on a fun vacation. If you’re looking for a tropical getaway, the Panama Canal warm waters and lively islands are the ultimate place for relaxation.

Panama Canal

Looking for Panama Canal cruise out of Miami, Florida in 2022? Take a memorable cruise adventure out of Miami, Florida to Panama Canal. Traversing the 40-mile Panama Canal is a rite of passage and something you'll remember this Panama Canal cruise for a lifetime. On your Panama Canal cruise you'll venture deep into the Panamanian rain forest, meet the locals, and learn the inner workings of the fascinating Panama Canal's locks. Discover paradise islands, breathtaking scenery and natural wonders with cruise ships from MSC Cruises, Norwegian Cruise Line, Oceania Cruises, Seabourn, and other lines.


Calendars, Cruise Ship Itinerary and Schedule for Panama Canal cruise out of Miami 2022

Panama Canal are one of the most popular cruise destinations in the world. With miles of stellar beaches, chic shops, luxurious resorts, quaint towns, and friendly people, it’s easy to see why travelers come from around the globe to experience this place. On Panama Canal cruises you can combine a glamorous vacation at an upscale resort with the charming allure of a small town. Boasting one of the world’s largest underwater cave systems, three national parks, endless beaches and crisp blue water, Panama Canal has it all.

Cruise Name Cruise Line Cruise Ship Duration Date

10-day Panama Canal cruise from Miami

MSC Cruises MSC Divina 10 day November 4, 2022
Ports of Call: Miami, At Sea, Ocho Rios, At Sea, Cartagena, Colon, Puerto Limon, At Sea, At Sea, Ocean Cay, Miami.

14-day Panama Canal Quest from Miami

Seabourn Seabourn Quest 14 day November 11, 2022
Ports of Call: Miami, Key West, At Sea, Belize, Trujillo, At Sea, Bocas Del Toro, Panama Canal, At Sea, Puntarenas, Puerto Caldera, San Juan Del Sur, Quepos, At Sea, Panama City.

10-day Panama Canal cruise from Miami

MSC Cruises MSC Divina 10 day November 18, 2022
Ports of Call: Miami, At Sea, Ocho Rios, At Sea, Cartagena, Colon, Puerto Limon, At Sea, At Sea, Ocean Cay, Miami.

11-day Panama Canal cruise from Miami

Norwegian Cruise Line Norwegian Pearl 11 day November 18, 2022
Ports of Call: Miami, At Sea, Grand Cayman, Ocho Rios, At Sea, Panama Canal, Colon, Puerto Limon, At Sea, Harvest Caye, Cozumel, At Sea, Miami.

11-day Panama Canal cruise from Miami

Norwegian Cruise Line Norwegian Pearl 11 day November 29, 2022
Ports of Call: Miami, At Sea, Grand Cayman, At Sea, Cartagena, Panama Canal, Colon, Puerto Limon, At Sea, Harvest Caye, Cozumel, At Sea, Miami.

10-day Panama Canal cruise from Miami

MSC Cruises MSC Divina 10 day December 2, 2022
Ports of Call: Miami, At Sea, Ocho Rios, At Sea, Cartagena, Colon, Puerto Limon, At Sea, At Sea, Ocean Cay, Miami.

14-day Panama Canal Quest from Miami

Seabourn Seabourn Quest 14 day December 9, 2022
Ports of Call: Miami, Key West, At Sea, Belize, Trujillo, At Sea, Bocas Del Toro, Panama Canal, At Sea, Puntarenas, Puerto Caldera, San Juan Del Sur, Quepos, At Sea, Panama City.

11-day Panama Canal cruise from Miami

Norwegian Cruise Line Norwegian Pearl 11 day December 10, 2022
Ports of Call: Miami, At Sea, Grand Cayman, Ocho Rios, At Sea, Panama Canal, Colon, Puerto Limon, At Sea, Harvest Caye, Cozumel, At Sea, Miami.

12-day Panama Canal cruise from Miami

Norwegian Cruise Line Norwegian Pearl 12 day December 21, 2022
Ports of Call: Miami, At Sea, At Sea, Aruba, Curacao, Bonaire, Santa Marta, Cartagena, Panama Canal, Colon, Puerto Limon, At Sea, At Sea, Miami.

18-day Golden Gala from Miami

Oceania Cruises Insignia 18 day December 28, 2022
Ports of Call: Miami, At Sea, Grand Cayman, At Sea, Cartagena, Panama Canal, At Sea, San Juan Del Sur, Acajutla, Puerto Chiapas, At Sea, Manzanillo, Puerto Vallarta, Mazatlan, Cabo San Lucas, At Sea, San Diego, At Sea, San Francisco.

10-day Panama Canal cruise from Miami

MSC Cruises MSC Divina 10 day December 30, 2022
Ports of Call: Miami, Ocean Cay, At Sea, Ocho Rios, At Sea, Cartagena, Colon, Puerto Limon, At Sea, At Sea, Miami.

11-day Panama Canal cruise from Miami

Norwegian Cruise Line Norwegian Pearl 11 day January 2, 2023
Ports of Call: Miami, At Sea, Grand Cayman, At Sea, Cartagena, Panama Canal, Colon, Puerto Limon, At Sea, Harvest Caye, Cozumel, At Sea, Miami.

11-day Panama Canal cruise from Miami

Norwegian Cruise Line Norwegian Pearl 11 day January 16, 2023
Ports of Call: Miami, At Sea, Grand Cayman, Ocho Rios, At Sea, Panama Canal, Colon, Puerto Limon, At Sea, Harvest Caye, Cozumel, At Sea, Miami.

10-day Panama Potpourri from Miami

Oceania Cruises Sirena 10 day January 18, 2023
Ports of Call: Miami, Key West, At Sea, Costa Maya, Harvest Caye, Santo Tomas, Roatan, At Sea, Puerto Limon, Panama Canal, Panama City, Panama City.

10-day Panama Canal cruise from Miami

MSC Cruises MSC Divina 10 day February 24, 2023
Ports of Call: Miami, At Sea, Ocho Rios, At Sea, Cartagena, Colon, Puerto Limon, At Sea, At Sea, Ocean Cay, Miami.

10-day Panama Canal cruise from Miami

MSC Cruises MSC Divina 10 day March 24, 2023
Ports of Call: Miami, At Sea, Ocho Rios, At Sea, Cartagena, Colon, Puerto Limon, At Sea, At Sea, Ocean Cay, Miami.