Miami Cruises MIAMI CRUISES

16-day Panama Canal Cruise from Miami

Panama Canal

Enjoy a once-in-a-lifetime experience aboard a 16-day Panama Canal cruise that departs from Miami. From Miami, Florida, cruises to the Panama Canal visit both Central American and Caribbean locations. Crossing the Panama Canal by ship is a once-in-a-lifetime experience. While going to or coming from the Panama Canal, one of the greatest man-made wonders in the world, go deep into the Panamanian rain forest, meet the locals, and learn how the locks work. During your 16-day cruise through the Panama Canal, you will visit a wide variety of ports, and you will also have ample time at sea to take advantage of all of the incredible amenities and services that are offered on board, including world-class dining, luxurious staterooms, and cutting-edge lounges. Enjoy a Indulge in a 16-day trip from Miami to the islands of the Panama Canal, where you can relax in the warm water and soak up the sun.


Find and plan your next 16-day Panama Canal cruise out of Miami

Regent Seven Seas Cruises Panama Canal 16-day route

16-day Panama Canal from Miami

Seven Seas Grandeur, Regent Seven Seas Cruises

Date: December 13, 2024

Ports of Call: Miami, Grand Cayman, Cartagena, Panama Canal, Puntarenas, Corinto, Puerto Quetzal, Acapulco, Cabo San Lucas, Ensenada, Los Angeles; View Itinerary

Oceania Cruises Panama Canal 16-day route

16-day Panama Canal from Miami

Insignia, Oceania Cruises

Date: December 29, 2024

Ports of Call: Miami, Grand Cayman, Cartagena, Panama Canal, Puntarenas, Corinto, Puerto Quetzal, Acapulco, Cabo San Lucas, Ensenada, Los Angeles; View Itinerary

Azamara Club Cruises Panama Canal 16-day route

16-day Panama Canal from Miami

Azamara Journey, Azamara Club Cruises

Date: January 7, 2025

Ports of Call: Miami, Key West, Grand Cayman, Puerto Limon, Cartagena, Cartagena, Panama Canal, Manta, Guayaquil, Trujillo, Lima, Lima; View Itinerary

Oceania Cruises Panama Canal 16-day route

16-day Panama Canal from Miami

Vista, Oceania Cruises

Date: January 8, 2025

Ports of Call: Miami, Grand Cayman, Cartagena, Panama Canal, Puntarenas, Corinto, Puerto Quetzal, Acapulco, Cabo San Lucas, Ensenada, Los Angeles; View Itinerary