Miami Cruises MIAMI CRUISES

21-day cruise from Miami

21-day cruise from Miami Take one of the 21-day cruises that set sail from Miami, Florida to really experience island life. Traveling to the Bahamas or the western, southern, or eastern Caribbean on one of these cruises will allow you to experience the region's countless nuances at your leisure. There's a Caribbean island perfect for you if you're looking for excitement like snorkeling and scuba diving or relaxation like beach reading and a frosty drink. Your 21-day cruise fee already includes your rooms, entertainment, and food, so it won't be difficult for you to learn what it means to truly relax throughout your voyage. Whether you enjoy adventure activities like snorkeling and scuba diving or prefer more laid-back activities like beach reading and sipping a chilled beverage, there is a tropical island right for you.

21-day destinations out of Miami

Discover the diverse range of exciting destinations you can visit on 21-day cruises departing from PortMiami, offering unique experiences and adventures in the Caribbean and beyond.

  • Venture to the Southern Caribbean to uncover hidden gems with less-traveled roads and intimate, peaceful islands. Explore cruises to Southern Caribbean.

Cruise lines departing from Miami

The world's most renowned cruise lines welcome cruisers at PortMiami, offering a variety of memorable 21-day cruise experiences.

21-day Cruise Itineraries and Schedule from Miami

A wonderful tropical vacation can be had by setting sail from Miami on a 21-day cruise. Take a 21-day tropical cruise out of Miami and explore the islands in the Southern Caribbean, all while soaking up the laid-back island vibe.

Price from: $ 10,801
latest updates:
For the latest updates about this itinerary, check at Regent Seven Seas Cruises website
View Itinerary

21-day
Southern Caribbean
cruise from Miami
onboard Seven Seas Mariner

Departure Date: Saturday, December 20, 2025

Regent Seven Seas Cruises Southern Caribbean 21-day route to Aruba, Bonaire, Curacao, St. Georges, Castries, Pointe a Pitre, St. Kitts, Tortola, Miami, Cozumel, Roatan, Harvest Caye, Costa Maya

Line Name: Regent Seven Seas Cruises

Ship Name: Seven Seas Mariner

Duration: 21-day cruise

Cruise Type: Holiday cruise

Ports of Call: Miami (5:00pm), Aruba (10:00am-10:00pm), Bonaire (7:00am-7:00pm), Curacao (7:00am-7:00pm), St. Georges (7:00am-7:00pm), Castries (7:00am-9:00pm), Pointe a Pitre (7:00am-6:00pm), St. Kitts (8:00am-6:00pm), Tortola (7:00am-5:00pm), Miami (7:00am-7:00pm), Cozumel (7:00am-5:00pm), Roatan (9:00am-6:00pm), Harvest Caye (7:00am-5:00pm), Costa Maya (8:00am-5:00pm), Miami (7:00am);

© 2025 Miami Cruises.