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One-way Cruise from Miami

One-way One-way cruises from Miami, Florida sail from one destination to another across the Bahamas and Caribbean, departing from Miami and ending in another port. They offer a blend of exciting cities or ports you wouldn't see on other itineraries. Most one-way cruises are repositioning cruises, and because the ships spend so much time at sea, they often have very low prices.

Available destinations out of Miami

Discover the diverse range of exciting destinations you can visit on cruises departing from PortMiami, offering unique experiences and adventures in the Caribbean and beyond.

  • Witness the engineering marvel of the Panama Canal and explore the rich history and diverse ecosystems surrounding this iconic waterway. Explore cruises to Panama Canal.
  • Venture to the Southern Caribbean to uncover hidden gems with less-traveled roads and intimate, peaceful islands. Explore cruises to Southern Caribbean.

Cruise lines departing from Miami

At PortMiami, cruisers are welcomed by the world's most renowned cruise lines, offering a variety of memorable experiences.

  • Azamara Club Cruises: Embark on a luxurious journey in the Caribbean, where immersive experiences await you.
  • Carnival Cruise Line: Experience joy on fun-filled voyages suitable for all ages in the Caribbean.
  • Celebrity Cruises: Indulge in sophistication and refined experiences on Caribbean seas.
  • MSC Cruises: Elevate your Caribbean adventure with Mediterranean-inspired luxury and innovation.
  • Norwegian Cruise Line: Cruise the Caribbean on your terms with diverse entertainment and freestyle cruising.
  • Oceania Cruises: Indulge in exquisite cuisine and refined exploration in the breathtaking Caribbean.
  • Regent Seven Seas Cruises: Discover the epitome of all-inclusive luxury at sea.
  • Royal Caribbean: Choose immersive cruising in the Caribbean, where innovative ships and unforgettable adventures await.
  • Seabourn: Experience intimate luxury with extraordinary moments at sea as you sail through the Caribbean.
  • Virgin Voyages: Set sail on a rebellious journey with style, offering adult-only cruising.

Duration

There are a variety of Caribbean itineraries available from Miami, ranging from 2 to 21 days.

One-way Cruise Itineraries and Schedule from Miami

Price from: $ 3,618
latest updates:
For the latest updates about this itinerary, check at Oceania Cruises website
View Itinerary

10-day
Panama Canal
cruise from Miami
onboard Sirena

Departure Date: Saturday, February 8, 2025

Oceania Cruises Panama Canal 10-day route to Cozumel, Costa Maya, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal/Panama City

Line Name: Oceania Cruises

Ship Name: Sirena

Duration: 10-day cruise

Cruise Type: One-way cruise

Ports of Call: Miami (6:00pm), Cozumel (8:00am-6:00pm), Costa Maya (7:00am-5:00pm), Harvest Caye (7:00am-4:00pm), Santo Tomas (8:00am-9:00pm), Roatan (8:00am-6:00pm), Puerto Limon (8:00am-4:00pm), Panama Canal (8:00am-8:00pm), Panama City (8:00pm-11:59pm), Panama City (0:00am-8:00am);

Price from: $ 1,554
latest updates:
For the latest updates about this itinerary, check at Norwegian Cruise Line website
View Itinerary

10-day
Panama Canal
cruise from Miami
onboard Norwegian Jade

Departure Date: Friday, December 12, 2025

Norwegian Cruise Line Panama Canal 10-day route to Cozumel, Harvest Caye, Roatan, George Town, Cartagena, Colon, Panama Canal

Line Name: Norwegian Cruise Line

Ship Name: Norwegian Jade

Duration: 10-day cruise

Cruise Type: One-way cruise

Ports of Call: Miami (5:30pm), Cozumel (7:00am-5:00pm), Harvest Caye (11:00am-6:00pm), Roatan (7:00am-2:00pm), George Town (10:30am-6:00pm), Cartagena (7:00am-4:00pm), Colon (8:00am-7:00pm), Panama Canal (At Sea), Panama City (3:00am);

Price from: $ 7,978
latest updates:
For the latest updates about this itinerary, check at Regent Seven Seas Cruises website
View Itinerary

12-day
Panama Canal
cruise from Miami
onboard Seven Seas Grandeur

Departure Date: Saturday, January 3, 2026

Regent Seven Seas Cruises Panama Canal 12-day route to George Town, Ocho Rios, Bonaire, Curacao, Aruba, Cartagena, Puerto Limon, Panama Canal

Line Name: Regent Seven Seas Cruises

Ship Name: Seven Seas Grandeur

Duration: 12-day cruise

Cruise Type: One-way cruise

Ports of Call: Miami (5:00pm), George Town (9:00am-5:00pm), Ocho Rios (10:00am-6:00pm), Bonaire (10:00am-8:00pm), Curacao (7:00am-7:00pm), Aruba (7:00am-3:00pm), Cartagena (1:00pm-11:00pm), Puerto Limon (7:00am-4:00pm), Panama Canal (At Sea), Panama City (7:00am);

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