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Panama City from Miami 2026

Panama City, PanamaCruise to Panama City in 2026 from the Port of Miami, Florida. Numerous cruise ships departs from Miami cruise terminals throughout 2026, offering a top-quality itinerary to Panama City, Panama. There’s lots to see and do in Panama City, your only job is to find your little bit of heaven in this great cruise destination. The color of the sea is indescribable; it is calm; no waves; and the water is warm and clear. If you’re looking for a tropical getaway, Panama City’s warm waters are the ultimate place for relaxation.

Panama City Weather

    Panama City is best enjoyed from December to April, offering pleasant weather and fewer crowds.
  • Winter (December to February): Cool and dry, perfect for exploring.
  • Spring (March to May): Warm and sunny, great for outdoor activities.
  • Summer (June to August): Hot and humid, with occasional rain showers.
  • Fall (September to November): Warm with increased rainfall, especially in September and October.

Cruise Itineraries and Schedule from Miami to Panama City in 2026

Price from: $ 7,978
latest updates:
For the latest updates about this itinerary, check at Regent Seven Seas Cruises website
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12-day
Panama Canal
cruise from Miami
onboard Seven Seas Grandeur

Departure Date: Saturday, January 3, 2026

Regent Seven Seas Cruises Panama Canal 12-day route to George Town, Ocho Rios, Bonaire, Curacao, Aruba, Cartagena, Puerto Limon, Panama Canal

Line Name: Regent Seven Seas Cruises

Ship Name: Seven Seas Grandeur

Duration: 12-day cruise

Cruise Type: One-way cruise

Ports of Call: Miami (5:00pm), George Town (9:00am-5:00pm), Ocho Rios (10:00am-6:00pm), Bonaire (10:00am-8:00pm), Curacao (7:00am-7:00pm), Aruba (7:00am-3:00pm), Cartagena (1:00pm-11:00pm), Puerto Limon (7:00am-4:00pm), Panama Canal (At Sea), Panama City (7:00am);

Price from: $ 3,334
latest updates:
For the latest updates about this itinerary, check at Oceania Cruises website
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10-day
Western Caribbean
cruise from Miami
onboard Insignia

Departure Date: Tuesday, April 14, 2026

Oceania Cruises Western Caribbean 10-day route to Cozumel, Costa Maya, Belize City, Roatan, Puerto Limon, Colon, Panama Canal/Panama City

Line Name: Oceania Cruises

Ship Name: Insignia

Duration: 10-day cruise

Cruise Type: Roundtrip cruise

Ports of Call: Miami (5:00pm), Cozumel (7:00am-5:00pm), Costa Maya (7:00am-5:00pm), Belize City (8:00am-5:00pm), Roatan (7:00am-4:00pm), Puerto Limon (9:00am-7:00pm), Colon (10:00am-7:00pm), Panama Canal (8:00am-8:00pm), Panama City (8:00pm-11:59pm), Panama City (0:00am-8:00am);

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