12-day Eastern Caribbean Cruise from Miami

12-day Eastern Caribbean cruise from Miami offers an unforgettable journey featuring vibrant cultures, stunning beaches, and exciting excursions. A 12-day cruise from Miami, Florida, is the perfect option to make a short getaway feel like a much longer period of repose, offering you the chance to unwind without the hassle. The beauty of a 12-day Eastern, Western, or Southern Caribbean cruise is that you only have to unpack once and settle into one room, yet still experience a rich variety of cultures, landscapes, and destinations. On a 12-day cruise, you'll see a wide variety of Western, Southern, or Eastern Caribbean ports and have ample time at sea to enjoy all of the incredible amenities and services on board, from world-class dining to luxurious staterooms and innovative lounges.

Eastern Caribbean Ports of Call

Eastern Caribbean cruise from Miami include stops in some of the most breathtaking beaches and crystal-clear waters in the world.

• Antigua and Barbuda: Set sail from Miami to Antigua and Barbuda, where you'll find yourself lounging on some of the Caribbean's most stunning beaches and exploring historic naval fortifications.
• British Virgin Islands (BVI): The British Virgin Islands await cruise-goers from Miami with their unspoiled landscapes, exclusive resorts, and excellent sailing conditions.
• Dominica: Cruise from Miami to Dominica to experience its rugged natural beauty, with thermal springs and lush rainforests at every turn.
• Dominican Republic: From Miami, the Dominican Republic is a cruise destination known for its vibrant culture, historic architecture, and pristine beaches.
• Dutch Caribbean: The Dutch Caribbean offers a unique European flair, making it a favorite cruise route from Miami for those seeking both culture and beach relaxation.
• Guadeloupe: Guadeloupe, a cruise from Miami, entices with its French-Creole cuisine and the majestic La Soufrière volcano.
• Haiti: Haiti's rich culture and historic sites make it a compelling cruise stop from Miami, offering a deep dive into the roots of the Caribbean.
• Puerto Rico: Set sail from Miami to Puerto Rico, where historic San Juan and lush rainforests provide the backdrop for a perfect Caribbean adventure.
• St. Barts (Saint Barthelemy): St. Barts offers an exclusive getaway from Miami, known for its upscale shopping, white sandy beaches, and celebrity sightings.
• St. Kitts and Nevis: Explore the rich history and lush landscapes of St. Kitts and Nevis, a delightful cruise journey from Miami.
• Turks and Caicos archipelago: Turks and Caicos are renowned for their world-class beaches and coral reefs, making it a top cruise pick from Miami.
• US Virgin Islands (USVI): The US Virgin Islands, a short cruise from Miami, offer American charm combined with Caribbean beauty.

Cruise lines departing from Miami

At PortMiami, cruisers are welcomed by the world's most renowned cruise lines, offering a variety of Eastern Caribbean itineraries. Explore a 12-day cruise from Miami to multiple destinations.

• Azamara Club Cruises: Embark on a luxurious journey in the Caribbean, where immersive experiences await you.
• Carnival Cruise Line: Experience joy on fun-filled voyages suitable for all ages in the Caribbean.
• Celebrity Cruises: Indulge in sophistication and refined experiences on Caribbean seas.
• MSC Cruises: Elevate your Caribbean adventure with Mediterranean-inspired luxury and innovation.
• Norwegian Cruise Line: Cruise the Caribbean on your terms with diverse entertainment and freestyle cruising.
• Oceania Cruises: Indulge in exquisite cuisine and refined exploration in the breathtaking Caribbean.
• Regent Seven Seas Cruises: Discover the epitome of all-inclusive luxury at sea.
• Royal Caribbean: Choose immersive cruising in the Caribbean, where innovative ships and unforgettable adventures await.
• Seabourn: Experience intimate luxury with extraordinary moments at sea as you sail through the Caribbean.
• Virgin Voyages: Set sail on a rebellious journey with style, offering adult-only cruising.

During your 12-day cruise through the Eastern Caribbean, you will visit a wide variety of ports, and you will also have ample time at sea to take advantage of all of the incredible amenities and services that are offered on board, including world-class dining, luxurious staterooms, and cutting-edge lounges. Enjoy a Indulge in a 12-day trip from Miami to the islands of the Eastern Caribbean, where you can relax in the warm water and soak up the sun.

Price from: $ 5,046
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12-day
Southern Caribbean
cruise from Miami
onboard Vista

Departure Date: Thursday, March 27, 2025

Line Name: Oceania Cruises

Ship Name: Vista

Duration: 12-day cruise

Cruise Type: Roundtrip cruise

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Ports of Call: Miami (6:00pm), Aruba (10:00am-10:00pm), Curacao (6:00am-7:00pm), Bonaire (7:00am-2:00pm), St. Georges (1:00pm-9:00pm), Castries (8:00am-5:00pm), St. Kitts (8:00am-5:00pm), San Juan (7:00am-2:00pm), Great Stirrup Cay (10:00am-7:00pm), Miami (8:00am);

Price from: $ 1,662
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12-day
Southern Caribbean
cruise from Miami
onboard Norwegian Pearl

Departure Date: Monday, March 31, 2025

Line Name: Norwegian Cruise Line

Ship Name: Norwegian Pearl

Duration: 12-day cruise

Cruise Type: Roundtrip cruise

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Ports of Call: Miami (5:30pm), Puerto Plata (8:00am-4:00pm), Aruba (10:00am-10:00pm), Bonaire (8:00am-8:00pm), Curacao (6:00am-1:00pm), St. Thomas (12:00pm-8:00pm), St. Kitts (10:00am-5:00pm), San Juan (8:am-4:pm), Great Stirrup Cay (10:00am-6:00pm), Miami (7:00am);

Price from: $ 4,948
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12-day
Eastern Caribbean
cruise from Miami
onboard Vista

Departure Date: Saturday, April 19, 2025

Line Name: Oceania Cruises

Ship Name: Vista

Duration: 12-day cruise

Cruise Type: Roundtrip cruise

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Ports of Call: Miami (6:00pm), Great Stirrup Cay (7:00am-3:00pm), Royal Naval Dockyard (1:00pm-11:59pm), Royal Naval Dockyard (0:00am-11:59pm), Royal Naval Dockyard (0:00am-3:00pm), Charleston (1:00pm-11:59pm), Charleston (0:00am-6:00pm), Fernandina Beach (8:00am-6:00pm), Port Canaveral (7:00am-5:00pm), Nassau (9:00am-6:00pm), Miami (8:00am);

Price from: $ 5,449
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12-day
Eastern Caribbean
cruise from Miami
onboard Seabourn Sojourn

Departure Date: Thursday, November 13, 2025

Line Name: Seabourn

Ship Name: Seabourn Sojourn

Duration: 12-day cruise

Cruise Type: Roundtrip cruise

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Ports of Call: Miami (5:00pm), San Juan (8:00am-6:00pm), Gustavia (8:00am-6:00pm), Terre-de-Haut (8:00am-6:00pm), Roseau (8:00am-6:00pm), St. Kitts (8:00am-6:00pm), Great Harbour (7:00am-2:00pm), Miami (7:00am);

Price from: $ 4,370
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12-day
Southern Caribbean
cruise from Miami
onboard Allura

Departure Date: Sunday, November 16, 2025

Line Name: Oceania Cruises

Ship Name: Allura

Duration: 12-day cruise

Cruise Type: Roundtrip cruise

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Ports of Call: Miami (6:00pm), Aruba (10:00am-10:00pm), Curacao (7:00am-10:00pm), Bonaire (7:00am-1:00pm), St. Georges (1:00pm-9:00pm), Castries (7:00am-4:00pm), Gustavia (9:00am-7:00pm), Tortola (7:00am-5:00pm), Miami (8:00am);

Price from: $ 2,159
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12-day
Eastern Caribbean
cruise from Miami
onboard Azamara Onward

Departure Date: Sunday, November 30, 2025

Line Name: Azamara Club Cruises

Ship Name: Azamara Onward

Duration: 12-day cruise

Cruise Type: Roundtrip cruise

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Ports of Call: Miami (6:00pm), San Juan (9:00am-10:00pm), St. John (8:00am-6:00pm), St. Maarten (8:00am-10:00pm), Antigua (8:00am-6:00pm), St. Kitts (8:00am-6:00pm), Charlestown (8:00am-6:00pm), Virgin Gorda (8:00am-62:00pm), Miami (6:00am);

Price from: $ 6,670
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12-day
Eastern Caribbean
cruise from Miami
onboard Seven Seas Grandeur

Departure Date: Monday, December 22, 2025

Line Name: Regent Seven Seas Cruises

Ship Name: Seven Seas Grandeur

Duration: 12-day cruise

Cruise Type: Holiday cruise

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Ports of Call: Miami (5:00pm), St. Kitts (11:00am-8:00pm), Antigua (8:00am-6:00pm), Fort-De-France (8:00am-6:00pm), Bridgetown (8:00am-7:00pm), St. Georges (8:00am-8:00pm), Castries (7:00am-3:00pm), St. Maarten (9:00am-4:00pm), Miami (7:00am);

Price from: $ 5,057
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12-day
Eastern Caribbean
cruise from Miami
onboard Allura

Departure Date: Friday, January 16, 2026

Line Name: Oceania Cruises

Ship Name: Allura

Duration: 12-day cruise

Cruise Type: Roundtrip cruise

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Ports of Call: Miami (5:00pm), San Juan (7:00am-5:00pm), Tortola (7:00am-5:00pm), St. Croix (7:00am-5:00pm), St. Kitts (7:00am-5:00pm), Pointe a Pitre (7:00am-5:00pm), Antigua (7:00am-5:00pm), St. Thomas (7:00am-5:00pm), Miami (8:00am);