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12-day Southern Caribbean Cruise from Miami

Southern Caribbean12-day Southern Caribbean cruise from Miami offers an unforgettable journey featuring vibrant cultures, stunning beaches, and exciting excursions. A 12-day cruise from Miami, Florida, is the perfect option to make a short getaway feel like a much longer period of repose, offering you the chance to unwind without the hassle. The beauty of a 12-day Eastern, Western, or Southern Caribbean cruise is that you only have to unpack once and settle into one room, yet still experience a rich variety of cultures, landscapes, and destinations. On a 12-day cruise, you'll see a wide variety of Western, Southern, or Eastern Caribbean ports and have ample time at sea to enjoy all of the incredible amenities and services on board, from world-class dining to luxurious staterooms and innovative lounges.

Southern Caribbean Ports of Call

Southern Caribbean cruise from Miami include stops in some of the most breathtaking beaches and crystal-clear waters in the world.

  • ABC Islands: Cruises from Miami to the ABC Islands promise a blend of Dutch charm and Caribbean warmth, perfect for travelers seeking both adventure and relaxation.
  • Barbados: From Miami, head to Barbados, where British heritage meets Caribbean beauty, complete with exquisite beaches and lush botanical gardens.
  • Grenada: Known as the 'Spice Isle,' Grenada offers cruises from Miami to its fragrant nutmeg groves and stunning waterfalls.
  • Martinique: Martinique brings a taste of French elegance to the Caribbean, easily accessible via cruises from Miami.
  • Saint Lucia: From Miami, Saint Lucia is just a cruise away, ready to enchant you with its iconic Piton mountains and luxurious hot springs.
  • Saint Vincent and the Grenadines: Sail from Miami to Saint Vincent and the Grenadines, a haven of secluded beaches and crystal-clear waters, perfect for yacht cruising.
  • Trinidad and Tobago: Vibrant festivals and diverse wildlife make Trinidad and Tobago a compelling cruise destination from Miami.

Cruise lines departing from Miami

At PortMiami, cruisers are welcomed by the world's most renowned cruise lines, offering a variety of Southern Caribbean itineraries. Explore a 12-day cruise from Miami to multiple destinations.

  • Carnival Cruise Line: Experience joy on fun-filled voyages suitable for all ages in the Caribbean.
  • Norwegian Cruise Line: Cruise the Caribbean on your terms with diverse entertainment and freestyle cruising.
  • Oceania Cruises: Indulge in exquisite cuisine and refined exploration in the breathtaking Caribbean.
  • Regent Seven Seas Cruises: Discover the epitome of all-inclusive luxury at sea.
  • Seabourn: Experience intimate luxury with extraordinary moments at sea as you sail through the Caribbean.

12-day Southern Caribbean Itineraries and Cruise Schedule from Miami

During your 12-day cruise through the Southern Caribbean, you will visit a wide variety of ports, and you will also have ample time at sea to take advantage of all of the incredible amenities and services that are offered on board, including world-class dining, luxurious staterooms, and cutting-edge lounges. Enjoy a Indulge in a 12-day trip from Miami to the islands of the Southern Caribbean, where you can relax in the warm water and soak up the sun.

Price from: $ 6,670
latest updates:
For the latest updates about this itinerary, check at Regent Seven Seas Cruises website
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12-day
Eastern Caribbean
cruise from Miami
onboard Seven Seas Grandeur

Departure Date: Monday, December 22, 2025

Regent Seven Seas Cruises Eastern Caribbean 12-day route to St. Kitts, Antigua, Fort-De-France, Bridgetown, St. Georges, Castries, St. Maarten

Line Name: Regent Seven Seas Cruises

Ship Name: Seven Seas Grandeur

Duration: 12-day cruise

Cruise Type: Holiday cruise

Ports of Call: Miami (5:00pm), St. Kitts (11:00am-8:00pm), Antigua (8:00am-6:00pm), Fort-De-France (8:00am-6:00pm), Bridgetown (8:00am-7:00pm), St. Georges (8:00am-8:00pm), Castries (7:00am-3:00pm), St. Maarten (9:00am-4:00pm), Miami (7:00am);

Price from: $ 7,978
latest updates:
For the latest updates about this itinerary, check at Regent Seven Seas Cruises website
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12-day
Panama Canal
cruise from Miami
onboard Seven Seas Grandeur

Departure Date: Saturday, January 3, 2026

Regent Seven Seas Cruises Panama Canal 12-day route to George Town, Ocho Rios, Bonaire, Curacao, Aruba, Cartagena, Puerto Limon, Panama Canal

Line Name: Regent Seven Seas Cruises

Ship Name: Seven Seas Grandeur

Duration: 12-day cruise

Cruise Type: One-way cruise

Ports of Call: Miami (5:00pm), George Town (9:00am-5:00pm), Ocho Rios (10:00am-6:00pm), Bonaire (10:00am-8:00pm), Curacao (7:00am-7:00pm), Aruba (7:00am-3:00pm), Cartagena (1:00pm-11:00pm), Puerto Limon (7:00am-4:00pm), Panama Canal (At Sea), Panama City (7:00am);

Price from: $ 3,858
latest updates:
For the latest updates about this itinerary, check at Oceania Cruises website
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12-day
Southern Caribbean
cruise from Miami
onboard Insignia

Departure Date: Thursday, January 15, 2026

Oceania Cruises Southern Caribbean 12-day route to Aruba, Curacao, Port of Spain, St. Georges, Castries, Kingstown, Roseau, Fort-de-France

Line Name: Oceania Cruises

Ship Name: Insignia

Duration: 12-day cruise

Cruise Type: Roundtrip cruise

Ports of Call: Miami (5:00pm), Aruba (11:00am-10:00pm), Curacao (7:00am-5:00pm), Port of Spain (7:00am-5:00pm), St. Georges (7:00am-5:00pm), Castries (7:00am-5:00pm), Kingstown (7:00am-5:00pm), Roseau (7:00am-5:00pm), Fort-de-France (7:00am-5:00pm), Bridgetown (8:0am);

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