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21-day Southern Caribbean Cruise from Miami

Southern Caribbean21-day Southern Caribbean cruise from Miami offers an unforgettable journey featuring vibrant cultures, stunning beaches, and exciting excursions. Take one of the 21-day cruises that set sail from Miami, Florida to really experience island life. Traveling to the Bahamas or the western, southern, or eastern Caribbean on one of these cruises will allow you to experience the region's countless nuances at your leisure. There's a Caribbean island perfect for you if you're looking for excitement like snorkeling and scuba diving or relaxation like beach reading and a frosty drink. Your 21-day cruise fee already includes your rooms, entertainment, and food, so it won't be difficult for you to learn what it means to truly relax throughout your voyage.

Southern Caribbean Ports of Call

Southern Caribbean cruise from Miami include stops in some of the most breathtaking beaches and crystal-clear waters in the world.

  • ABC Islands: Cruises from Miami to the ABC Islands promise a blend of Dutch charm and Caribbean warmth, perfect for travelers seeking both adventure and relaxation.
  • Barbados: From Miami, head to Barbados, where British heritage meets Caribbean beauty, complete with exquisite beaches and lush botanical gardens.
  • Grenada: Known as the 'Spice Isle,' Grenada offers cruises from Miami to its fragrant nutmeg groves and stunning waterfalls.
  • Martinique: Martinique brings a taste of French elegance to the Caribbean, easily accessible via cruises from Miami.
  • Saint Lucia: From Miami, Saint Lucia is just a cruise away, ready to enchant you with its iconic Piton mountains and luxurious hot springs.
  • Saint Vincent and the Grenadines: Sail from Miami to Saint Vincent and the Grenadines, a haven of secluded beaches and crystal-clear waters, perfect for yacht cruising.
  • Trinidad and Tobago: Vibrant festivals and diverse wildlife make Trinidad and Tobago a compelling cruise destination from Miami.

Cruise lines departing from Miami

At PortMiami, cruisers are welcomed by the world's most renowned cruise lines, offering a variety of Southern Caribbean itineraries. Explore a 21-day cruise from Miami to multiple destinations.

  • Azamara Club Cruises: Embark on a luxurious journey in the Caribbean, where immersive experiences await you.
  • Carnival Cruise Line: Experience joy on fun-filled voyages suitable for all ages in the Caribbean.
  • MSC Cruises: Elevate your Caribbean adventure with Mediterranean-inspired luxury and innovation.
  • Norwegian Cruise Line: Cruise the Caribbean on your terms with diverse entertainment and freestyle cruising.
  • Oceania Cruises: Indulge in exquisite cuisine and refined exploration in the breathtaking Caribbean.
  • Regent Seven Seas Cruises: Discover the epitome of all-inclusive luxury at sea.
  • Royal Caribbean: Choose immersive cruising in the Caribbean, where innovative ships and unforgettable adventures await.
  • Seabourn: Experience intimate luxury with extraordinary moments at sea as you sail through the Caribbean.

21-day Southern Caribbean Itineraries and Cruise Schedule from Miami

During your 21-day cruise through the Southern Caribbean, you will visit a wide variety of ports, and you will also have ample time at sea to take advantage of all of the incredible amenities and services that are offered on board, including world-class dining, luxurious staterooms, and cutting-edge lounges. Enjoy a Indulge in a 21-day trip from Miami to the islands of the Southern Caribbean, where you can relax in the warm water and soak up the sun.

Price from: $ 10,801
latest updates:

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View Itinerary

21-day
Southern Caribbean
cruise from Miami
onboard Seven Seas Mariner

Date: Saturday, December 20, 2025

Regent Seven Seas Cruises Southern Caribbean 21-day route to Aruba, Bonaire, Curacao, St. Georges, Castries, Pointe a Pitre, St. Kitts, Tortola, Miami, Cozumel, Roatan, Harvest Caye, Costa Maya

Line Name: Regent Seven Seas Cruises

Ship Name: Seven Seas Mariner

Duration: 21-day cruise

Cruise Type: Holiday cruise


Ports of Call: Miami (5:00pm), Aruba (10:00am-10:00pm), Bonaire (7:00am-7:00pm), Curacao (7:00am-7:00pm), St. Georges (7:00am-7:00pm), Castries (7:00am-9:00pm), Pointe a Pitre (7:00am-6:00pm), St. Kitts (8:00am-6:00pm), Tortola (7:00am-5:00pm), Miami (7:00am-7:00pm), Cozumel (7:00am-5:00pm), Roatan (9:00am-6:00pm), Harvest Caye (7:00am-5:00pm), Costa Maya (8:00am-5:00pm), Miami (7:00am);