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12-day Western Caribbean Cruise from Miami

Western Caribbean12-day Western Caribbean cruise from Miami offers an unforgettable journey featuring vibrant cultures, stunning beaches, and exciting excursions. A 12-day cruise from Miami, Florida, is the perfect option to make a short getaway feel like a much longer period of repose, offering you the chance to unwind without the hassle. The beauty of a 12-day Eastern, Western, or Southern Caribbean cruise is that you only have to unpack once and settle into one room, yet still experience a rich variety of cultures, landscapes, and destinations. On a 12-day cruise, you'll see a wide variety of Western, Southern, or Eastern Caribbean ports and have ample time at sea to enjoy all of the incredible amenities and services on board, from world-class dining to luxurious staterooms and innovative lounges.

Western Caribbean Ports of Call

Western Caribbean cruise from Miami include stops in some of the most breathtaking beaches and crystal-clear waters in the world.

  • Belize: Cruises from Miami to Belize offer the chance to explore ancient Mayan ruins and dive into the world's second-largest barrier reef.
  • Cayman Islands: The Cayman Islands, a luxurious cruise destination from Miami, are known for their spectacular diving sites and refined culinary scene.
  • Colombia: Sail from Miami to Colombia's vibrant coastline, where rich history and breathtaking landscapes provide an unforgettable adventure.
  • Costa Rica: Costa Rica's lush rainforests and rich biodiversity are just a cruise away from Miami, offering eco-adventurers a paradise to explore.
  • Guatemala: Embark from Miami to Guatemala, where you can explore ancient Mayan civilizations and vibrant colonial towns.
  • Honduras: From Miami, cruise to Honduras to explore its rich marine life and ancient Mayan ruins nestled in lush landscapes.
  • Jamaica: Jamaica's reggae rhythms and stunning landscapes await just a cruise away from Miami, offering a vibrant mix of music, cuisine, and adventure.
  • Mexico: Cruises from Miami to Mexico invite you to discover ancient Mayan ruins, bustling beach resorts, and vibrant cultural festivals.

Cruise lines departing from Miami

At PortMiami, cruisers are welcomed by the world's most renowned cruise lines, offering a variety of Western Caribbean itineraries. Explore a 12-day cruise from Miami to multiple destinations.

  • Azamara Club Cruises: Embark on a luxurious journey in the Caribbean, where immersive experiences await you.
  • Carnival Cruise Line: Experience joy on fun-filled voyages suitable for all ages in the Caribbean.
  • Celebrity Cruises: Indulge in sophistication and refined experiences on Caribbean seas.
  • MSC Cruises: Elevate your Caribbean adventure with Mediterranean-inspired luxury and innovation.
  • Norwegian Cruise Line: Cruise the Caribbean on your terms with diverse entertainment and freestyle cruising.
  • Oceania Cruises: Indulge in exquisite cuisine and refined exploration in the breathtaking Caribbean.
  • Regent Seven Seas Cruises: Discover the epitome of all-inclusive luxury at sea.
  • Royal Caribbean: Choose immersive cruising in the Caribbean, where innovative ships and unforgettable adventures await.
  • Virgin Voyages: Set sail on a rebellious journey with style, offering adult-only cruising.

12-day Western Caribbean Itineraries and Cruise Schedule from Miami

During your 12-day cruise through the Western Caribbean, you will visit a wide variety of ports, and you will also have ample time at sea to take advantage of all of the incredible amenities and services that are offered on board, including world-class dining, luxurious staterooms, and cutting-edge lounges. Enjoy a Indulge in a 12-day trip from Miami to the islands of the Western Caribbean, where you can relax in the warm water and soak up the sun.

Price from: $ 4,130
latest updates:

For the latest updates about this itinerary, check at Oceania Cruises website
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12-day
Western Caribbean
cruise from Miami
onboard Vista

Departure Date: Thursday, December 5, 2024

Oceania Cruises Western Caribbean 12-day route to Cozumel, Costa Maya, Santo Tomas, Harvest Caye, Roatan, George Town, Montego Bay, Great Stirrup Cay

Line Name: Oceania Cruises

Ship Name: Vista

Duration: 12-day cruise

Cruise Type: Roundtrip cruise


Ports of Call: Miami (6:00pm), Cozumel (7:00am-4:00pm), Costa Maya (8:00am-6:00pm), Santo Tomas (8:00am-9:00pm), Harvest Caye (7:00am-5:00pm), Roatan (8:00am-6:00pm), George Town (7:00am-5:00pm), Montego Bay (7:00am-4:00pm), Great Stirrup Cay (9:00am-6:00pm), Miami (8:00am);

Price from: $ 7,978
latest updates:

For the latest updates about this itinerary, check at Regent Seven Seas Cruises website
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12-day
Panama Canal
cruise from Miami
onboard Seven Seas Grandeur

Departure Date: Saturday, January 3, 2026

Regent Seven Seas Cruises Panama Canal 12-day route to George Town, Ocho Rios, Bonaire, Curacao, Aruba, Cartagena, Puerto Limon, Panama Canal

Line Name: Regent Seven Seas Cruises

Ship Name: Seven Seas Grandeur

Duration: 12-day cruise

Cruise Type: One-way cruise


Ports of Call: Miami (5:00pm), George Town (9:00am-5:00pm), Ocho Rios (10:00am-6:00pm), Bonaire (10:00am-8:00pm), Curacao (7:00am-7:00pm), Aruba (7:00am-3:00pm), Cartagena (1:00pm-11:00pm), Puerto Limon (7:00am-4:00pm), Panama Canal (At Sea), Panama City (7:00am);

Price from: $ 5,057
latest updates:

For the latest updates about this itinerary, check at Oceania Cruises website
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12-day
Western Caribbean
cruise from Miami
onboard Allura

Departure Date: Sunday, January 4, 2026

Oceania Cruises Western Caribbean 12-day route to Cozumel, Costa Maya, Belize City, Santo Tomas, Roatan, Montego Bay, George Town, Key West

Line Name: Oceania Cruises

Ship Name: Allura

Duration: 12-day cruise

Cruise Type: Roundtrip cruise


Ports of Call: Miami (7:00pm), Cozumel (7:00am-5:00pm), Costa Maya (7:00am-5:00pm), Belize City (8:00am-5:00pm), Santo Tomas (7:00am-5:00pm), Roatan (7:00am-5:00pm), Montego Bay (7:00am-4:00pm), George Town (7:00am-6:00pm), Key West (7:00am-6:00pm), Miami (8:00am);

Price from: $ 7,476
latest updates:

For the latest updates about this itinerary, check at Regent Seven Seas Cruises website
View Itinerary

12-day
Western Caribbean
cruise from Miami
onboard Seven Seas Grandeur

Departure Date: Saturday, March 14, 2026

Regent Seven Seas Cruises Western Caribbean 12-day route to Key West, Cozumel, Cozumel, Costa Maya, Santo Tomas, Harvest Caye, Roatan, Ocho Rios, George Town

Line Name: Regent Seven Seas Cruises

Ship Name: Seven Seas Grandeur

Duration: 12-day cruise

Cruise Type: Roundtrip cruise


Ports of Call: Miami (5:00pm), Key West (7:00am-3:00pm), Cozumel (2:00pm-11:59pm), Cozumel (0:00am-9:00pm), Costa Maya (8:00pm-6:00pm), Santo Tomas (8:00am-6:00pm), Harvest Caye (8:00am-6:00pm), Roatan (8:00am-6:00pm), Ocho Rios (7:00am-3:00pm), George Town (7:00am-3:00pm), Miami (7:00am);