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Panama Canal One-way Cruise from Miami

One-wayPanama Canal One-way cruises from Miami, Florida have gained significant popularity. One-way cruises from Miami, Florida sail from one destination to another across the Bahamas and Caribbean, departing from Miami and ending in another port. They offer a blend of exciting cities or ports you wouldn't see on other itineraries. Most one-way cruises are repositioning cruises, and because the ships spend so much time at sea, they often have very low prices.

Panama Canal Ports of Call

Panama Canal cruise from Miami include stops in some of the most breathtaking beaches and crystal-clear waters in the world.

  • Panama: A Miami departure to Panama offers the unique experience of cruising through the iconic Panama Canal and exploring its surrounding tropical biodiversity.

Cruise lines departing from Miami

At PortMiami, cruisers are welcomed by the world's most renowned cruise lines, offering a variety of Panama Canal itineraries.

  • Azamara Club Cruises: Embark on a luxurious journey in the Caribbean, where immersive experiences await you.
  • Norwegian Cruise Line: Cruise the Caribbean on your terms with diverse entertainment and freestyle cruising.
  • Oceania Cruises: Indulge in exquisite cuisine and refined exploration in the breathtaking Caribbean.
  • Regent Seven Seas Cruises: Discover the epitome of all-inclusive luxury at sea.
  • Royal Caribbean: Choose immersive cruising in the Caribbean, where innovative ships and unforgettable adventures await.

Duration

There are a variety of Tropical itineraries available from Miami, ranging from 7 to 14 days.

Panama Canal One-way Itineraries and Cruise Schedule from Miami

Price from: $ 1,900
latest updates:
For the latest updates about this itinerary, check at Azamara Club Cruises website
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10-day
Panama Canal
cruise from Miami
onboard Azamara Journey

Departure Date: Tuesday, December 3, 2024

Azamara Club Cruises Panama Canal 10-day route to Aruba, Bonaire, Curacao, Cartagena, Cartagena, Panama Canal/Panama City

Line Name: Azamara Club Cruises

Ship Name: Azamara Journey

Duration: 10-day cruise

Cruise Type: One-way cruise

Ports of Call: Miami (5:00pm), Aruba (1:00pm-10:00pm), Bonaire (8:00am-10:00pm), Curacao (8:00am-10:00pm), Cartagena (8:00am-11:59pm), Cartagena (00:00am-12:00pm), Panama Canal (5:00am-5:00pm), Panama City (5:00pm-11:59pm), Panama City (0:00am 7:00pm);

Price from: $ 4,588
latest updates:
For the latest updates about this itinerary, check at Oceania Cruises website
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14-day
Southern Caribbean
cruise from Miami
onboard Sirena

Departure Date: Saturday, December 21, 2024

Oceania Cruises Southern Caribbean 14-day route to Costa Maya, Harvest Caye, Roatan, Puerto Limon, Colon, Cartagena, Curacao, Aruba, Castries

Line Name: Oceania Cruises

Ship Name: Sirena

Duration: 14-day cruise

Cruise Type: Holiday cruise

Ports of Call: Miami (6:00pm), Costa Maya (9:00am-6:00pm), Harvest Caye (8:00am-5:00pm), Roatan (7:00am-5:00pm), Puerto Limon (8:00am-5:00pm), Colon (7:00am-5:00pm), Cartagena (11:00am-10:00pm), Curacao (8:00am-10:00pm), Aruba (7:00am-6:00pm), Castries (8:00am-7:00pm), Bridgetown (8:00am);

Price from: $ 3,618
latest updates:
For the latest updates about this itinerary, check at Oceania Cruises website
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10-day
Panama Canal
cruise from Miami
onboard Sirena

Departure Date: Saturday, February 8, 2025

Oceania Cruises Panama Canal 10-day route to Cozumel, Costa Maya, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal/Panama City

Line Name: Oceania Cruises

Ship Name: Sirena

Duration: 10-day cruise

Cruise Type: One-way cruise

Ports of Call: Miami (6:00pm), Cozumel (8:00am-6:00pm), Costa Maya (7:00am-5:00pm), Harvest Caye (7:00am-4:00pm), Santo Tomas (8:00am-9:00pm), Roatan (8:00am-6:00pm), Puerto Limon (8:00am-4:00pm), Panama Canal (8:00am-8:00pm), Panama City (8:00pm-11:59pm), Panama City (0:00am-8:00am);

Price from: $ 1,554
latest updates:
For the latest updates about this itinerary, check at Norwegian Cruise Line website
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10-day
Panama Canal
cruise from Miami
onboard Norwegian Jade

Departure Date: Friday, December 12, 2025

Norwegian Cruise Line Panama Canal 10-day route to Cozumel, Harvest Caye, Roatan, George Town, Cartagena, Colon, Panama Canal

Line Name: Norwegian Cruise Line

Ship Name: Norwegian Jade

Duration: 10-day cruise

Cruise Type: One-way cruise

Ports of Call: Miami (5:30pm), Cozumel (7:00am-5:00pm), Harvest Caye (11:00am-6:00pm), Roatan (7:00am-2:00pm), George Town (10:30am-6:00pm), Cartagena (7:00am-4:00pm), Colon (8:00am-7:00pm), Panama Canal (At Sea), Panama City (3:00am);

Price from: $ 7,978
latest updates:
For the latest updates about this itinerary, check at Regent Seven Seas Cruises website
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12-day
Panama Canal
cruise from Miami
onboard Seven Seas Grandeur

Departure Date: Saturday, January 3, 2026

Regent Seven Seas Cruises Panama Canal 12-day route to George Town, Ocho Rios, Bonaire, Curacao, Aruba, Cartagena, Puerto Limon, Panama Canal

Line Name: Regent Seven Seas Cruises

Ship Name: Seven Seas Grandeur

Duration: 12-day cruise

Cruise Type: One-way cruise

Ports of Call: Miami (5:00pm), George Town (9:00am-5:00pm), Ocho Rios (10:00am-6:00pm), Bonaire (10:00am-8:00pm), Curacao (7:00am-7:00pm), Aruba (7:00am-3:00pm), Cartagena (1:00pm-11:00pm), Puerto Limon (7:00am-4:00pm), Panama Canal (At Sea), Panama City (7:00am);

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